In a video shared online, tearful Chanice Cushion urged Brits to stay indoors to halt the spread of Covid-19.
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The mum, who works at Southend Hospital in Essex, can't see her little girl for the next three months to protect her from potentially catching the deadly bug.
In the film, posted on Facebook yesterday, she revealed she and her partner made the decision for her to move out because they live with her high-risk mother-in-law – who has chronic asthma – as well as their tot.
She welled up as she said her daughter was "going about her day as normal" as she packed to leave.
Chanice said: "She's a two-year-old, she doesn't understand.
"I left home earlier, and I said 'mummy's going away for a little while. Mummy's got work.'
"And she said, 'Mummy, I come'.
"I said 'no baby, you can't. I said I'm going to Nanny's house and Nanny's going to stay here with you.'
"So today's my first day of 12 weeks away from my kid, and it's very hard.
"So I said my goodbyes to her and, as a normal parent would do, started to cry.
"She just looked at me and went 'Mummy, why are you sad'. I didn't know how to answer it, so I just replied with 'Mummy is sad'.
"She grabbed her sleeve and she was wiping my tears away with her sleeve and said 'don't cry Mummy.'"
The video has been shared more than 80,000 times online, and she has received thousands of comments of support.
Breaking down into tears, Chanice added: "I've had to leave my daughter for three months because I don't want to put her in that vulnerable situation.
"She has no idea what's going on.
"No idea at all."
Chanice says she is petrified of going in to work.
She said hospital staff are "basically suspecting anyone" who comes through the doors with either a cough or temperature of having coronavirus.
It comes as Britain's death toll soared again , with 54 more people confirmed yesterday to have died after testing positive for coronavirus.
So far, 336 people have died of the disease in the UK, with confirmed cases jumping from 6,650 to 6,710 today.
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Last night, Boris Johnson announced a nationwide lockdown in a bid to stop the virus's advance.
Heroic NHS workers on the UK's coronavirus frontline have also begged Brits to stay at home to protect lives.
Medical staff in Belfast battling the disease release a video warning “this is not a rehearsal".
But there are fears that building sites remaining open and packed London tubes will put NHS staff at risk.
One NHS trauma surgeon sent a desperate text to BBC News host Sophie Raworth saying: “All builders are still at work!
“Clogging roads and Tubes.
“They need to know that we won’t be able to do [the] usual heroic salvage of limbs when they have the inevitable industrial accidents."
I'm petrified of going to work – I'm petrified – but I have to go to work.
Medical emergency assistant Chanice pleaded for Brits to "stay indoors".
She said: "I'm petrified of going to work – I'm petrified – but I have to go to work.
"You have to stay indoors. There is nothing so special out there for you to be going out.
"Yeah, the sun's shining – you might be dead in a few weeks because you wanted to go out and get some fresh air and mingle with people and not keep a two-metre distance.
"You need to really get your priorities straight. Go home, stay home, protect your children, protect the vulnerable people that you could potentially be infecting.
"Shelves are being stripped of fruit, veg, meat. I even struggled to get eggs.
"It just seems so surreal. How are the NHS workers supposed to stay healthy and fit when we've got nothing to feed us, we've got nothing to build our energy.
"Just stay indoors and if you need to come out, one person come out from a family and go do what they've got to do, then go straight home.
"Get straight in the shower, wash your hands for 20 seconds. You need to be so vigilant guys."